嘉兴学院生物与化学工程学院
李蕾
1985年07月毕业于江西师范大学化学系。1985-2005年在赣南师范大学化学系工作,2003年晋升教授。2005年入职嘉兴学院,现为应用化学系二级教授,“南湖学者”特聘教授。主持完成国家自然科学基金面上项目、浙江省重点科技计划项目等省部级课题20余项。在Chem.Sci.、Anal.Chem.、Chem. Commun.、ACS Sensors、 Biosens. Bioelectron.、Sensor. Actuat. B: Chem.、Anal. Chim. Acta、Analyst、Talanta、Microchim. Acta等期刊上发表论文100余篇,其中在SCI期刊上发表研究论文80余篇;申请国家发明专利30余项,其中授权发明专利20余项。指导已毕业硕士研究生60余名。
联系方式:lei.li@zjxu.edu.cn
研究领域:
1. 分子识别与分离分析技术;2. 微纳功能材料与分析检测技术。
主持项目(近五年):
1.基于烯基离子液体的磁性分子印迹固相萃取及其在芳香胺检测中的应用研究(国家自然科学基金面上项目, No. 21677060)
2.基于双功能烯基染料离子液体的分子印迹荧光传感器构建策略及其检测硝基酚类化合物的研究(浙江省自然科学基金面上项目, No. LY20B050009)
3.农产品中含潜在高危隐患因子的快速捕集与超高灵敏检测关键技术研究(浙江省科技厅公益技术项目, No. 2015C32067)
4.电纺丝纳米纤维-分子印迹膜在环境样品前处理中的应用研究(国家自然科学基金面上项目,No. 21177049)
5.基于烯基离子液体的磁性分子印迹固相萃取技术应用基础研究(浙江省自然科学基金委一般项目,No. LY16B050007)
代表性论文(近三年):
X. Lu, L. Wang, Q. Chen, Y. Wang, Z. Cao, G. Zhou*, L. Li*, A biosensor based on multifunctional allostery for dynamic analysis of circulating tumor DNA, Chem. Commun., 2020, 56, 4184-4187.
X. Lu, G. Zhou, J. Zhang, W. Xie, Y. Yang*, Y. Zeng, Z. Zhang, H. Wang, L. Li*, Highly sensitive determination of 2,4,6-trichlorophenol by using a novel SiO2@MIPIL fluorescence sensor with a double recognition functional monomer, ACS Sensors, 2020, 5, 1445-1454.
H. Dai, Z. Deng, Y. Zeng*, J. Zhang, Y. Yang, Q. Ma, W. Hu, L. Guo, L. Li*, S. Wan, H. Liu, Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid), J. Hazard. Mater., 2020, 398, 122854.
Y. Lu, J. Hu, Y. Zeng*, Y. Zhu, H. Wang, X. Lei, S. Huang, L. Guo, L. Li*, Electrochemical determination of rutin based on molecularly imprinted poly (ionic liquid) with ionic liquid-graphene as a sensitive element, Sensor. Actuat. B: Chem., 2020, 311, 127911.
W. Xie, J. Zhang, Y. Zeng, H. Wang, Y. Yang*, Y. Zhai, D. Miao, L. Li*, Highly sensitive and selective detection of 4-nitroaniline in water by a novel fluorescent sensor based on molecularly imprinted poly(ionic liquid), Anal. Bioanal. Chem., 2020, 412: 5653-5661.
D. Miao, D. Liu, Y. Zeng, G. Zhou, W. Xie, Y. Yang*, H. Wang, J. Zhang, Y. Zhai, Z. Zhang, L. Li*, Fluorescent aptasensor based on D-AMA/F-CSC for the sensitive andspecific recognition of myoglobin, Spectrochim. Acta A, 2020, 228, 117714.
X. Lu, G. Zhou*, Y. Zeng, Z. Yin , Z. Zhang , L. Guo, Y. Zhai , Y. Yang , H. Wang, L. Li*, Single-step multivalent capture assay for nucleic acid detection with dual-affinity regulation using mutation inhibition and allosteric activation,Chem. Sci., 2019, 10, 5025-5030.
X. Lu, G. Zhou*, Y. Lu, L. Li*, Stem-loop clutch probes for sequence-specific dsDNA analysis with improved single-mismatch selectivity, Chem. Commun., 2019, 55, 7514-7517.
J. Hu, H. Dai, Y. Zeng*, Y. Yang, H. Wang, X. Zhu, L. Li*, G. Zhou, R. Chen*, L. Guo, A cross-linker-based poly(ionic liquid) for sensitive electrochemical detection of 4-nonylphenol, Nanomaterials, 2019, 9, 513.
X. Tang, Z. Yin*, X. Lei, Y. Zeng, Z. Zhang, Y. Lu, G. Zhou, L. Li*, X. Wu*, Colorimetric method for sensitive detection of microcystin-lr using surface copper nanoparticles of polydopamine nanosphere as turn-on probe, Nanomaterials, 2019, 9, 332.
D. Liu, Y. Zeng, G. Zhou, X. Lu, D. Miao, Y. Yang*, Y. Zhai, J. Zhang, Z. Zhang, H. Wang, L. Li*, Fluorometric determination of cardiac myoglobin based on energy transfer from a pyrene-labeled aptamer to graphene oxide, Microchim. Acta, 2019, 186, 287.
Y. Wang, K. Yu, M. Tian, L. Li, Z. Zhang*, L. Li*, A versatile strategy to fabricate magnetic dummy molecularly imprinted mesoporous silica particles for specific magnetic separation of bisphenol A. New J. Chem., 2019, 43, 3400-3408.
Y. Yang, Y. Zeng*, C.i Tang, X. Zhu, X. Lu, L. Liu, Z. Chen, L. Li*, Voltammetric determination of 5-hydroxytryptamine based on the use of platinum nanoparticles coated with molecularly imprinted silica, Microchim. Acta, 2018, 185(4), 219.
X. Zhu, Y. Zeng*, Z. Zhang, Y. Yang, Y. Zhai, H. Wang, L. Liu, J. Hu, L. Li*, A new composite of graphene and molecularly imprinted polymer based on ionic liquids as functional monomer and cross-linker for electrochemical sensing 6-benzylaminopurine,Biosens. Bioelectron., 2018, 108, 38-45.
H. Yan, X. Tang, X. Zhu, Y. Zeng*, X. Lu, Z. Yin, Y. Lu, Y. Yang, L. Li*, Sandwich-type electrochemical immunosensor for highly sensitive determination of cardiac troponin I using carboxyl-terminated ionic liquid and helical carbon nanotube composite as platform and ferrocenecarboxylic acid as signal label, Sensor. Actuat. B: Chem., 2018, 277, 234-240.
X. Lu, Y. Yang, Y. Zeng, L. Li*, X. Wu*, Rapid and reliable determination of p-nitroaniline in wastewater by molecularly imprinted fluorescent polymeric ionic liquid microspheres,Biosens. Bioelectron., 2018, 99, 47-55.
Z. Yin*, S. Cheng, L. Xu, H. Liu, K. Huang, L. Li*, Y. Zhai, Y. Zeng, H. Liu, Y. Shao*, Z. Zhang, Y. Lu. Highly sensitive and selective sensor for sunset yellow based on molecularly imprinted polydopamine-coated multi-walled carbon nanotubes, Biosens. Bioelectron., 2018, 100, 565-570.
Z. Zhang*, H. Wang, H. Wang, C. Wu, M. Li, L. Li*, Fabrication and evaluation of molecularly imprinted magnetic nanoparticles for elective recognition and magnetic separation of lysozyme in human urine. Analyst, 2018, 143, 5849-5856.